In Demonology 101, an adopted demon girl named Raven tries to deal with friends and high school while an epic struggle between the dark Powers that Be and a resistance group called the Network takes place. The entire story arc is complete, so there is no need to wait for the next episode. There is, however, an ongoing spinoff. Stylish two-tone artwork with touches of color, a solid sci-fi story, and some nice worldbuilding all go into making NYC2123 worth the read. The story takes place in a grim cyberpunk future Manhattan, surrounded by the Wall and ruled by martial law, surrounded by floating, lawless barge-cities that are operated by organized crime.
The DM of the Rings is an excellent webcomic. Though it's created entirely from movie stills, it hits comedic notes that anyone who's played D&D will recognize. Imagine a gaggle of modern hack-n-slash AD&D roleplayers who had somehow never been exposed to the original Tolkien mythos, and then imagine taking those players and trying to introduce them to Tolkien via a D&D campaign. The gamers are easily distracted, obsessed with loot, and have a tendency to quote Monty Python at the drop of a d8. The frustrated DM tries to keep the party on the rails, and the players fight against the railroading. All in all, I think I've gamed with all these people before.